I can't assure anything ....
i can tell you i used it when having Plist damage and worked, but was not a tampered drive but a damaged.
anyway if you backup all system files you can rewrite them back if you need.
this is the explanation about this option:
... the Format Client Defect List will be written with contents of the Active Error Log and the option to process the Client Defect List will be enabled. If there is no Active Error Log or there are no R/W-related entries in the Active Error Log, then this bit will be ignored
so this should rebuild PLIST as a first step ...
Let me know